STI Guide

Gonorrhea

A bacterial STI affecting the genitals, rectum, and throat. Rates are rising significantly in the US. Antibiotic resistance makes early diagnosis and proper treatment more important than ever.

Neisseria gonorrhoeae

Gonorrhea is caused by the bacterium Neisseria gonorrhoeae. It is the second most commonly reported bacterial STI in the US and can infect the genitals, rectum, throat, and eyes. Pharyngeal (throat) gonorrhea is particularly common and rarely causes symptoms. Resistance to antibiotics is an increasing public health concern, making testing and appropriate treatment essential.

Testing window2 weeks after exposure
CurableYes — dual antibiotic therapy
Sites of infectionGenitals, rectum, throat, eyes
Asymptomatic (throat)Usually no symptoms
Test typeNAAT swab or urine

Key facts about Gonorrhea

Gonorrhea can infect the throat, rectum, and eyes — not just the genitals.

Throat gonorrhea rarely causes symptoms and is often missed without testing.

Resistance to antibiotics is a serious and growing concern globally.

Treatment requires dual antibiotic therapy (ceftriaxone injection).

Untreated gonorrhea can spread to the bloodstream, causing serious illness.

Test-of-cure is recommended 2 weeks after treatment to confirm eradication.

How is gonorrhea transmitted?

Gonorrhea is spread through unprotected vaginal, anal, or oral sex with an infected person. It can infect any mucous membrane it comes into contact with — meaning throat infections from oral sex are common and often have no symptoms. It is not transmitted through toilet seats, sharing utensils, or casual contact.

What are the symptoms of gonorrhea?

In men, symptoms typically include a thick yellow or green discharge from the penis, a burning sensation when urinating, and inflammation of the foreskin. In women, symptoms may include an unusual vaginal discharge, burning when urinating, and lower abdominal pain — though many women have no symptoms. Rectal infection can cause discharge, pain, or bleeding. Throat infection almost never causes symptoms.

Testing for gonorrhea

Testing is performed using nucleic acid amplification tests (NAAT) on swabs from the urethra, cervix, rectum, or throat, or on a urine sample. It is important to test all sites that have been at risk, not just the genitals. If you have had oral sex, a throat swab is recommended. Results are typically available within a few days.

Treatment and antibiotic resistance

Gonorrhea is treated with a single intramuscular injection of ceftriaxone. Oral antibiotics alone are no longer recommended due to rising resistance. A test-of-cure appointment 2 weeks after treatment is standard practice. If you are diagnosed, recent partners should be informed and tested. Avoid all sexual contact until treatment is confirmed successful.

Complications of untreated gonorrhea

If left untreated, gonorrhea can spread beyond the genital tract. In women, this can cause pelvic inflammatory disease (PID), leading to chronic pelvic pain, ectopic pregnancy, or infertility. In men, it can cause epididymitis. In rare cases, the infection can spread via the bloodstream, causing septic arthritis, skin lesions, and — in severe cases — life-threatening complications.

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