STI Guide

HPV

Human Papillomavirus is the most common sexually transmitted infection in the world. Most infections clear without causing any problems. Vaccination before sexual activity is the best protection.

Human Papillomavirus

HPV is a group of more than 200 related viruses, of which around 40 infect the genital area. Most sexually active people will acquire HPV at some point in their lives. The majority of infections cause no symptoms and clear naturally within 1–2 years. Some strains cause genital warts; others are linked to cancers of the cervix, anus, penis, throat, and vulva.

PrevalenceMost sexually active people
Vaccine availableYes — Gardasil 9 (9 strains)
High-risk strainsHPV 16 and 18 (70% of cervical cancers)
Low-risk strainsHPV 6 and 11 (90% of genital warts)
TestingNo routine test for adults

Key facts about HPV

Most HPV infections are cleared by the immune system within 1–2 years.

HPV vaccination (Gardasil 9) protects against the strains responsible for most cancers and warts.

There is no routine HPV test available for adults who are not in a screening programme.

Cervical screening (smear test) detects HPV and abnormal cell changes — attend when invited.

Condoms reduce (but do not eliminate) HPV transmission as the virus is present on skin around the genitals.

Having HPV does not mean you or your partner has been unfaithful — it can remain dormant for years.

High-risk and low-risk HPV

Not all HPV strains are equal. Low-risk strains — particularly HPV 6 and 11 — cause genital warts but are not associated with cancer. High-risk strains — particularly HPV 16 and 18 — are linked to cervical, anal, penile, oropharyngeal, vulval, and vaginal cancers. Most high-risk infections still clear on their own; it is persistent infection with high-risk strains that poses a cancer risk.

Genital warts

Genital warts are soft, flesh-coloured growths that appear on or around the genitals and anus. They are caused by low-risk strains of HPV (primarily 6 and 11) and are not associated with cancer. They can be treated with topical creams, cryotherapy, or surgical removal, though they may recur. The presence of genital warts does not indicate a high-risk HPV infection.

HPV vaccination

The Gardasil 9 vaccine protects against HPV types 6, 11, 16, 18, 31, 33, 45, 52, and 58 — covering the strains responsible for most HPV-related cancers and genital warts. In the UK, the vaccine is offered routinely to adolescents. It is most effective when given before any sexual activity. Adults up to age 45 may benefit from vaccination — discuss with a healthcare provider.

Cervical screening and HPV

Cervical screening (the smear test) in the UK now tests for high-risk HPV first. If HPV is found, cells are examined for abnormalities. Most people with HPV will have normal cells and will be asked to attend their next routine screen. Abnormal cells (not cancer) may need monitoring or treatment. Attending cervical screening as invited is one of the most important things a person with a cervix can do to prevent cervical cancer.

Telling a partner about HPV

Because HPV is so common, has no routine test for adults, and often clears without either person knowing, partner notification is generally not recommended in the same way as it is for other STIs. However, it is reasonable to discuss vaccination status with a new partner. If you have been diagnosed with genital warts or high-risk HPV through a screening programme, speaking with your healthcare provider about disclosure is advisable.

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